#1 Brand for Brain Health
30,000+ Happy Customers
Clinical-Grade
Third-Party Certified
Daniel G. Amen, MD
Founder & Chief Visionary Officer, BrainMD
Dr. Daniel Amen is a double board-certified psychiatrist, 20-time national bestselling author, and one of the most influential voices in brain health. He’s the founder of Amen Clinics, home to the world’s largest database of brain scans related to behavior, with over 300,000 scans and counting.
Through his groundbreaking research, bestselling books, and BrainMD’s doctor-developed supplements, Dr. Amen has helped millions improve their memory, mood, focus, and mental well-being.
Make your brain and body happy!Happy Saffron Plus® combines clinically studied doses of award-winning affron® saffron extract, Longvida® curcumin, and zinc glycinate in their most bioavailable and efficacious forms to help improve your mood, memory, sexual function, and more.*
#1 For Brain Health
Backed by 30+ years of research, 60+ MDs & 300,000+ brain scans.*
Doctor-Recommended
Formulated by Dr. Daniel Amen and leading brain health experts.
Clinically Backed
Clinically studied ingredients. Backed by science. Proven to work.
HSA/FSA Eligible
Use pre-tax dollars to support your brain, body, and daily health.
Expert Reviews
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"This is one of my favorite formulas. Saffron has been studied for centuries, but the form we use—affron®—is backed by modern clinical trials. I take Happy Saffron Plus® daily because it works. Better mood, better memory, better overall brain health—naturally."
Dr. Daniel Amen
Founder, BrainMD & Amen Clinics
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"This formula contains ingredients I used to recommend individually but BrainMD combines them in clinically validated doses for even better results. I’ve seen it help patients feel more emotionally balanced and mentally sharp within weeks."
Dr. Jonny Bowden PhD, CNS
Board Certified Nutrition Specialist
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"Saffron has long been used in ancient medicine, but affron® takes it to a new level. It’s clinically backed, bioavailable, and when paired with Longvida® curcumin and zinc glycinate, it becomes a powerhouse for brain health and emotional wellness."
Peggy Perez
Brain Health Professional, NASM CPT & CES, IIS Health Coach
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"I love Happy Saffron Plus®! I was able to be off all anxiety/depression medications after 23 years. It works on multiple levels—mood, focus, and energy. It’s NAME-developed, rooted in science, and something I recommend regularly to my clients."
Erica Williams
Brain Health Professional, Elite Brain Health Coach, Life Coaching & Consulting Associates
